Cisplatin
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LUX-Lung 3, which compares the investigational oral, once-daily therapy, afatinib, to pemetrexed/cisplatin, is the largest Phase III trial to date in first-line EGFR mutation-positive, advanced, metastatic NSCLC patients, and the first to use ...
May 16, 2012 at 23:38 | Source: Marketwatch
The company said that the 2nd-line study enrolled 53 patients who had progressed on at least one prior chemotherapy regimen that included a platinum compound (cisplatin, oxaliplatin, or carboplatin) and a fluoropyrimidine (5-fluorouracil, capecitabine ...
May 24, 2012 at 16:55 | Source: RTT News
We will use one or two drugs from the following list: cisplatin, gemcitabine, vinorelbine, taxane, cetuximab and bevacizumab. If it is an adenocarcinoma (another kind of lung cancer) with a good activating mutation (what is called EGFR positive), we use ...
May 20, 2012 at 00:39 | Source: star.com.my
Researchers have shown before that that human copper transporter 1 (hCTR1) protein also participates in transport of the platinum-containing cisplatin, one of the most widely used anti-cancer drugs. Once platinum-containing cisplatin molecules ...
May 17, 2012 at 20:31 | Source: phys.org
This 2nd-line study enrolled 53 patients who had progressed on at least one prior chemotherapy regimen that included a platinum compound (cisplatin, oxaliplatin, or carboplatin) and a fluoropyrimidine (5-fluorouracil, capecitabine [Xeloda(R ...
May 24, 2012 at 10:35 | Source: Marketwatch
Mets were identified to the liver and to the peritoneum. I've been on chemo since then - first cisplatin + gemcitibine (which didn't shrink the masses) and then 12 rounds of folfirinox (oxaliplatin + irenotecan + 5fu pump). With that regime the masses were ...
May 24, 2012 at 20:30 | Source: American Cancer Society
The same pump transports the platinum-containing drug cisplatin into cancer cells to help kill them. Igor Tsigelny, a research scientist at the university's San Diego Supercomputer Centre and Department of Neurosciences, is lead author of the paper.
May 19, 2012 at 12:22 | Source: domain-b.com
ERCC1 expression was assessed by immunohistochemistry. ERCC1 expression was analyzed in 57 patients treated with adjuvant gemcitabine plus cisplatin chemotherapy and 36 who were not treated. Among 93 patients, ERCC1 expression was positive in 54 (58.1% ...
May 22, 2012 at 06:42 | Source: BioMed Central
"We knew some of the variables that might contribute to survival in metastatic bladder cancer patients treated with cisplatin-based chemotherapy, but we wanted to validate those findings and develop a definitive predictive model for treatment ...
May 19, 2012 at 03:46 | Source: News-Medical.Net